BDBM411040 N-[4-(2-Cyano-phenyl)-pyridin-3-yl]-N-methyl-3,5-bis-trifluoromethyl-benzamide::US10385022, Example 36

SMILES CN(C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnccc1-c1ccccc1C#N

InChI Key InChIKey=NUANEJSKNXMMKB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411040   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411040(N-[4-(2-Cyano-phenyl)-pyridin-3-yl]-N-methyl-3,5-b...)
Affinity DataEC50:  362nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent