BDBM411271 N-[4-(2-Benzyloxy-4-fluoro-phenyl)-pyridin-3-yl]-3-methanesulfonyl-N-methyl-5-trifluoromethyl-benzamide::US10385022, Example 267

SMILES CN(C(=O)c1cc(cc(c1)S(C)(=O)=O)C(F)(F)F)c1cnccc1-c1ccc(F)cc1OCc1ccccc1

InChI Key InChIKey=FYNDVLHOVCGNQE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411271   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411271(N-[4-(2-Benzyloxy-4-fluoro-phenyl)-pyridin-3-yl]-3...)
Affinity DataEC50:  3.46E+3nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent