BDBM411308 3-(1,1-Dioxo-thiomorpholine-4-sulfonyl)-N-[4-(4-fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-methyl-5-trifluoromethyl-benzamide::US10385022, Example 304

SMILES COc1cc(F)ccc1-c1ccncc1N(C)C(=O)c1cc(cc(c1)S(=O)(=O)N1CCS(=O)(=O)CC1)C(F)(F)F

InChI Key InChIKey=NBSYNGDRNOZBJP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411308   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411308(3-(1,1-Dioxo-thiomorpholine-4-sulfonyl)-N-[4-(4-fl...)
Affinity DataEC50:  15nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent