BDBM411396 4-Fluoro-N-(1-methyl-3-(1-(3- methylbutanoyl)piperidin-4-yl)-1H-indol-5- yl)benzenesulfonamide::US10385036, Example 12

SMILES CC(C)CC(=O)N1CCC(CC1)c1cn(C)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12

InChI Key InChIKey=ZJRDZYYUVWYEJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411396   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM411396(4-Fluoro-N-(1-methyl-3-(1-(3- methylbutanoyl)piper...)
Affinity DataIC50:  7.80nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent