BDBM411405 Preparation of N-(3-((2S,4R)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl)-1-methyl-1H-indol-5-yl)-4-fluorobenzenesulfonamide::US10385036, Example 21

SMILES C[C@H]1C[C@@H](CCN1C(=O)C1CCCC1)c1cn(C)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12

InChI Key InChIKey=RHMSENQWNDPSQM-AZUAARDMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411405   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM411405(Preparation of N-(3-((2S,4R)-1-(cyclopentanecarbon...)
Affinity DataIC50:  9nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent