BDBM412132 US10392402, Compound ID 40::US10807966, Compound 40

SMILES COc1cccc(CNC(=O)c2cc3ccc(nc3s2)-c2cn[nH]c2)c1

InChI Key InChIKey=YCKSAEMFWYPXDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 412132   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412132(US10392402, Compound ID 40 | US10807966, Compound ...)
Affinity DataIC50:  65.1nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412132(US10392402, Compound ID 40 | US10807966, Compound ...)
Affinity DataIC50:  17nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412132(US10392402, Compound ID 40 | US10807966, Compound ...)
Affinity DataIC50:  164nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412132(US10392402, Compound ID 40 | US10807966, Compound ...)
Affinity DataIC50:  17.4nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent