BDBM412135 US10392402, Compound ID 52::US10807966, Compound 52

SMILES COc1cccc(c1)[C@@H](C)NC(=O)Nc1cc(n[nH]1)-c1ccncc1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 412135   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412135(US10392402, Compound ID 52 | US10807966, Compound ...)
Affinity DataIC50:  34nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412135(US10392402, Compound ID 52 | US10807966, Compound ...)
Affinity DataIC50:  8.70nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412135(US10392402, Compound ID 52 | US10807966, Compound ...)
Affinity DataIC50:  34nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412135(US10392402, Compound ID 52 | US10807966, Compound ...)
Affinity DataIC50:  8.70nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent