BDBM412148 US10392405, Compound Id 1.012::US11059834, Compound 1.012::US11691985, Compound 1.012
SMILES Cc1c(COc2cc3OCCCCC(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1
InChI Key InChIKey=GHIPQHNIBMKRLS-NDEPHWFRSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 412148
Affinity DataIC50: 110nMAssay Description:Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS...More data for this Ligand-Target Pair
Ligand Info
TargetProgrammed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E](Homo sapiens (Human))
Chemocentryx
US Patent
Chemocentryx
US Patent
Affinity DataIC50: 300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 300nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info