BDBM412150 US10392405, Compound Id 1.014::US11059834, Compound 1.014::US11691985, Compound 1.014

SMILES OC(=O)[C@@H]1CCCCNC(=O)c2cncc(COc3cc(O[C@H]4CCc5c4cccc5-c4ccc5OCCOc5c4F)c(Cl)cc3CN1)c2

InChI Key InChIKey=VNGPJVIVPGRSFQ-KYJUHHDHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412150   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM412150(US10392405, Compound Id 1.014 | US11059834, Compou...)
Affinity DataIC50:  11nMAssay Description:Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM412150(US10392405, Compound Id 1.014 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM412150(US10392405, Compound Id 1.014 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent