BDBM412152 US10392405, Compound Id 1.016::US11059834, Compound 1.016::US11691985, Compound 1.016

SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1

InChI Key InChIKey=JQZKRMVVPDVDCE-PMERELPUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412152   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM412152(US10392405, Compound Id 1.016 | US11059834, Compou...)
Affinity DataIC50:  11nMAssay Description:Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM412152(US10392405, Compound Id 1.016 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM412152(US10392405, Compound Id 1.016 | US11059834, Compou...)
Affinity DataIC50: <100nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent