BDBM412210 US10398703, Compound 57::US10966987, Compound 57

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(CN(C)CCO)c4)c(Cl)c3)c2cc1OC

InChI Key InChIKey=OOZJOGKFFWVVDR-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412210   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM412210(US10398703, Compound 57 | US10966987, Compound 57)
Affinity DataKd:  1.30E+3nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM412210(US10398703, Compound 57 | US10966987, Compound 57)
Affinity DataKd:  1.30E+3nMAssay Description:A competition binding assay (DISCOVERX KINOMESCAN™) was used to measure the ability of a compound to compete for binding of an immobilized adenosine ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent