BDBM412282 US10399945, Example 21

SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)C(C)(C)C)-c1ccccc1

InChI Key InChIKey=RBLFRPZIYRJSRX-GGXMVOPNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412282   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412282(US10399945, Example 21)
Affinity DataIC50: <50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent