BDBM412359 US10399961, Example 3

SMILES Nc1ccc2C(CCc2n1)NC(=O)c1cn(Cc2ccc(cc2)C(F)c2ccon2)nn1

InChI Key InChIKey=SRPFSQFHTWHXEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412359   

TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM412359(US10399961, Example 3)
Affinity DataIC50:  5.50E+3nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 hr at Room Temperature with 0.10...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent