BDBM412371 US10399961, Example 16

SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)N[C@@H]4CCc5nc(N)ccc45)c(n3)C(F)(F)F)cc2)c1

InChI Key InChIKey=GYYMWPJBNBSMIW-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412371   

TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM412371(US10399961, Example 16)
Affinity DataIC50:  18nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 hr at Room Temperature with 0.10...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent