BDBM412419 N-(5-(2-chloro-5-(pyridin-2- yloxy)phenyl)pyrazin-2-yl)-4- methylnicotinamide::US10399967, Compound 49

SMILES Cc1ccncc1C(=O)Nc1cnc(cn1)-c1cc(Oc2ccccn2)ccc1Cl

InChI Key InChIKey=WQXPJLXSBWEPJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412419   

TargetInterleukin-2(Homo sapiens (Human))
Prcl Research

US Patent
LigandPNGBDBM412419(N-(5-(2-chloro-5-(pyridin-2- yloxy)phenyl)pyrazin-...)
Affinity DataIC50:  45nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent