BDBM412743 N-(3-fluoropyridin-4-yl)-2-(pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine::US10399987, Example 8
SMILES Fc1cnccc1Nc1nc(nc2[nH]ccc12)-c1ccccn1
InChI Key InChIKey=OFFLEANUVDDEBL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 412743
Affinity DataIC50: 150nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar
Ligand Info
Affinity DataIC50: 0.260nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand Info