BDBM412953 US10406157, Compound Formula 1

SMILES CC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC3CCOC3)nc2C1

InChI Key InChIKey=HSWVJQBEXRKOBZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412953   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412953(US10406157, Compound Formula 1)
Affinity DataKi:  5.5nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412953(US10406157, Compound Formula 1)
Affinity DataIC50:  1.97E+3nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent