BDBM413163 (S)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl)pyridin-2-yl)-5-hydroxy-1H-pyrazol-4-yl)-2-fluoro-3-methylbenzonitrile::US10407409, Example 328

SMILES CCN1CCN(C[C@@H]1C)C(=O)c1ccc(nc1)-n1ncc(c1O)-c1ccc(C#N)c(F)c1C

InChI Key InChIKey=SCUUFDLZFXDHAW-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413163   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413163((S)-4-(1-(5-(4-ethyl-3-methylpiperazine-1-carbonyl...)
Affinity DataIC50:  4.07nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent