BDBM413194 6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide::US10407409, Example 406

SMILES COCCCNC(=O)c1ccc(nc1)-n1ncc(c1O)-c1ccc(C#N)c(F)c1C

InChI Key InChIKey=ATRJUOIKMASCGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413194   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413194(6-(4-(4-cyano-3-fluoro-2-methylphenyl)-5-hydroxy-1...)
Affinity DataIC50:  3.24nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent