BDBM413199 (R)-2-fluoro-4-(5-hydroxy-1-(5-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)pyridin-2-yl)-1H-pyrazol-4-yl)-3-methylbenzonitrile::US10407409, Example 334

SMILES Cc1c(F)c(ccc1-c1cnn(c1O)-c1ccc(cn1)C(=O)N1CCN2CCC[C@@H]2C1)C#N

InChI Key InChIKey=XCCJFAIABOVJJP-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413199   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413199((R)-2-fluoro-4-(5-hydroxy-1-(5-(octahydropyrrolo[1...)
Affinity DataIC50:  3.16nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent