BDBM413406 US10407423, Compound 2-13

SMILES COc1cc2c3NC(CC4CCN(C)CC4)CCc3c(nc2cc1OCCCN1CCCC1)-c1cc(C)oc1C

InChI Key InChIKey=XJDVAWFCJARGSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413406   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
FundaciÓN Para La InvestigaciÓN MÉDica Aplicada

US Patent
LigandPNGBDBM413406(US10407423, Compound 2-13)
Affinity DataIC50:  5.50E+3nMAssay Description:The biochemical assay to measure DNMT1 enzyme activity relies on time-resolved fluorescence energy transfer (TR-FRET) between lumi4-Tb (donor) and d2...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
FundaciÓN Para La InvestigaciÓN MÉDica Aplicada

US Patent
LigandPNGBDBM413406(US10407423, Compound 2-13)
Affinity DataIC50: <100nMAssay Description:The biochemical assay to measure G9a enzyme activity relies on time-resolved fluorescence energy transfer (TR-FRET) between europium cryptate (donor)...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent