BDBM413419 US10407431, Example 6::ethyl 3-(3-((2-amino-4-(pentylamino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)methyl)-4-methoxyphenyl)propanoate

SMILES CCCCCNc1nc(N)nc2ccn(Cc3cc(CCC(=O)OCC)ccc3OC)c12

InChI Key InChIKey=CGJMKTBLNLYJHB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413419   

TargetToll-like receptor 7(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM413419(US10407431, Example 6 | ethyl 3-(3-((2-amino-4-(pe...)
Affinity DataEC50:  30nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent