BDBM413420 US10407431, Example 7::methyl 2-(3-((2-amino-4-(pentylamino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)methyl)-4-methoxyohenyl)-2,2-difluoroacetate

SMILES CCCCCNc1nc(N)nc2ccn(Cc3cc(ccc3OC)C(F)(F)C(=O)OC)c12

InChI Key InChIKey=DWUQECPGRFUAPF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413420   

TargetToll-like receptor 7(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM413420(US10407431, Example 7 | methyl 2-(3-((2-amino-4-(p...)
Affinity DataEC50:  100nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent