BDBM413429 2-(morpholin-4-yl)-2-oxoethyl (2E)-3-(3-{[2-amino-4-(pentylamino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]methyl}-4-methoxyphenyl)prop-2-enoate::US10407431, Example 16

SMILES CCCCCNc1nc(N)nc2ccn(Cc3cc(\C=C\C(=O)OCC(=O)N4CCOCC4)ccc3OC)c12

InChI Key InChIKey=QVOMNIZXHGDOSF-VQHVLOKHSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413429   

TargetToll-like receptor 7(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM413429(2-(morpholin-4-yl)-2-oxoethyl (2E)-3-(3-{[2-amino-...)
Affinity DataEC50: <5nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent