BDBM413512 US10414765, Example 4::[5-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl}hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl](6-methoxypyridin-2-yl)methanone

SMILES COc1cccc(n1)C(=O)N1CC2CN(Cc3c(nc4ccccn34)-c3ccc(Cl)cc3)CC2C1

InChI Key InChIKey=LMEIPAPPZIABHG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 413512   

TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413512(US10414765, Example 4 | [5-{[2-(4-Chlorophenyl)imi...)
Affinity DataIC50:  59.9nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413512(US10414765, Example 4 | [5-{[2-(4-Chlorophenyl)imi...)
Affinity DataIC50:  2.30E+3nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413512(US10414765, Example 4 | [5-{[2-(4-Chlorophenyl)imi...)
Affinity DataIC50:  947nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413512(US10414765, Example 4 | [5-{[2-(4-Chlorophenyl)imi...)
Affinity DataIC50:  256nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent