BDBM413554 US10414765, Example 36

SMILES FC(F)(F)c1cccc(OC(=O)N2CC3CN(Cc4c(nc5ccccn45)-c4ccc(Br)cc4)CC3C2)c1

InChI Key InChIKey=LUMLKNBQQCLLQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413554   

TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413554(US10414765, Example 36)
Affinity DataIC50:  450nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM413554(US10414765, Example 36)
Affinity DataIC50:  180nMAssay Description:In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis OocytesSub...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent