BDBM413973 US10421756, Compound 157

SMILES CC(C)COC(=O)N1CC2CN(CC2C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1

InChI Key InChIKey=CJBQCGLZWRMEOB-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413973   

TargetHistone deacetylase 1(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM413973(US10421756, Compound 157)
Affinity DataKd: <100nMAssay Description:HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM413973(US10421756, Compound 157)
Affinity DataKd:  300nMAssay Description:HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent