BDBM414008 US10421760, Comparative Example 8

SMILES C=CC(=O)NC1CCC=C(C1)c1ncnc2[nH]cc(-c3ncccn3)c12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414008   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414008(US10421760, Comparative Example 8)
Affinity DataIC50:  21.4nMAssay Description:JAK3: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM414008(US10421760, Comparative Example 8)
Affinity DataIC50: >1.00E+4nMAssay Description:JAK 2: Among materials for the measurement of this inhibiting activity, a substrate peptide and a kinase protein were acquired as follows. As such a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent