BDBM414027 1-methanesulfonyl-3- [(7R)-7-methyl-6-{1H- pyrrolo[2,3-b]pyridin-4- yl}-5H,6H,7H,8H- pyrido[4,3-d]pyrimidin-4- yl]piperidine::US10421765, Example 16::US10745420, Example 50a
SMILES C[C@@H]1Cc2ncnc(C3CCCN(C3)S(C)(=O)=O)c2CN1c1ccnc2[nH]ccc12
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 414027
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.57E+3nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 1.20E+3nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 3.57E+3nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair