BDBM414083 N-(3-((R)-7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-4-yl)-5,6,7,8- tetrahydropyrido[4,3-d]- pyrimidin-4-yl)-3-aza- bicyclo[3.2.1]octan-8-yl)- methanesulfonamide::US10421765, Example 69

SMILES C[C@@H]1Cc2ncnc(N3CC4CCC(C3)C4NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414083   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM414083(N-(3-((R)-7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-...)
Affinity DataIC50:  283nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent