BDBM414166 US10435369, Example 53

SMILES O[C@H](CNC(=O)[C@@H]1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=DWYVFCXUUIEWOX-UGGKCQTMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414166   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM414166(US10435369, Example 53)
Affinity DataIC50:  4nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent