BDBM414461 N-[6-Chloro-2-(tetrahydro-2H-pyran-4-yl)-2H-indazol-5-yl]-6-(difluoromethyl)pyridine-2-carboxamide::US10435396, Example 31

SMILES FC(F)c1cccc(n1)C(=O)Nc1cc2cn(nc2cc1Cl)C1CCOCC1

InChI Key InChIKey=SJUPOPAMQINQOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414461   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bayer Pharma Aktiegesellschaft

US Patent
LigandPNGBDBM414461(N-[6-Chloro-2-(tetrahydro-2H-pyran-4-yl)-2H-indazo...)
Affinity DataIC50:  22nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM solution of the test substance in DMSO....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent