BDBM414494 2-(1- cyanocyclopropyl)- N-ethyl-N-{2-[4-(1- hydroxy-1- methylethyl)-5- methyl-1,3-oxazol- 2- yl]ethyl}benzamide::US10435398, Example 10b

SMILES CCN(CCc1nc(c(C)o1)C(C)(C)O)C(=O)c1ccccc1C1(CC1)C#N

InChI Key InChIKey=YTHBZKIUFRLPPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414494   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414494(2-(1- cyanocyclopropyl)- N-ethyl-N-{2-[4-(1- hydro...)
Affinity DataIC50:  1.76E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414494(2-(1- cyanocyclopropyl)- N-ethyl-N-{2-[4-(1- hydro...)
Affinity DataIC50:  26nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent