BDBM414513 N-{2-[4-(1-Hydroxy-1-methylethyl)-5-methyl-1,3-oxazol-2-yl]ethyl}-N-(3-hydroxypropyl)-2-(2H-1,2,3-triazol-2-yl)benzamide::US10435398, Example 27

SMILES Cc1oc(CCN(CCCO)C(=O)c2ccccc2-n2nccn2)nc1C(C)(C)O

InChI Key InChIKey=ZEJTZNZYWJKEAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414513   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414513(N-{2-[4-(1-Hydroxy-1-methylethyl)-5-methyl-1,3-oxa...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM414513(N-{2-[4-(1-Hydroxy-1-methylethyl)-5-methyl-1,3-oxa...)
Affinity DataIC50:  304nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent