BDBM414536 US10435400, Compound Z-38
SMILES COc1cc(N2CCC(CC2)N(C)C)c(NC(=O)C=C)cc1Nc1ncc(OC)c(n1)-c1cnc2n(C)ncc2c1
InChI Key InChIKey=FNSYLKDWIHJNRH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414536
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
US Patent
Shanghai Haiyan Pharmaceutical Technology
US Patent
Affinity DataIC50: 35nMAssay Description:The inhibitory effects of compounds to be tested on double mutant EGFR kinase (EGFR T790M/L858R Kinase) (Invitrogen, PV4879) and wild-type EGFR kinas...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Shanghai Haiyan Pharmaceutical Technology
US Patent
Shanghai Haiyan Pharmaceutical Technology
US Patent
Affinity DataIC50: 16nMAssay Description:The inhibitory effects of compounds to be tested on double mutant EGFR kinase (EGFR T790M/L858R Kinase) (Invitrogen, PV4879) and wild-type EGFR kinas...More data for this Ligand-Target Pair