BDBM414709 US10435405, Example 126::US10934288, Example 126

SMILES Cn1cc(cn1)-c1n[nH]c2cnc(cc12)-c1c(F)cc(CNCCO)cc1F

InChI Key InChIKey=LDSUHSMFESJXMN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414709   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM414709(US10435405, Example 126 | US10934288, Example 126)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM414709(US10435405, Example 126 | US10934288, Example 126)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent