BDBM414742 US10435405, Example 159::US10934288, Example 159

SMILES CN1CCN(CC1)c1ccc(C(=O)Nc2n[nH]c3cnc(cc23)-c2c(C)cccc2F)c(NCc2ccnn2C)c1

InChI Key InChIKey=MQWKUHXRZCDJBV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414742   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM414742(US10435405, Example 159 | US10934288, Example 159)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM414742(US10435405, Example 159 | US10934288, Example 159)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent