BDBM415514 US10428074, Example 156

SMILES CN([C@@H]1C[C@H]2CN(C[C@H]2C1)C(=O)Nc1nc(O)ns1)c1ncnc2[nH]ccc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415514   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM415514(US10428074, Example 156)
Affinity DataIC50:  171nMAssay Description:JAK1: In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent