BDBM415539 (Scheme Z) (2S,3S,4R,5R)-2-((R)-1-hydroxyethyl)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (Z-2)::US10428104, Example 70

SMILES C[C@@H](O)[C@@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(C)ncnc12

InChI Key InChIKey=CGEZCGWQWJFBOB-XUEPZPCASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415539   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM415539((Scheme Z) (2S,3S,4R,5R)-2-((R)-1-hydroxyethyl)-5-...)
Affinity DataIC50:  50nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent