BDBM415571 (2R,3R,4S,5R)-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(4-fluorobenzyl)tetrahydrofuran-3,4-diol (ZZ-3)::US10428104, Example 101

SMILES Nc1ncnc2n(cc(F)c12)[C@@H]1O[C@H](Cc2ccc(F)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=TUAXRZOCPAKCDQ-LSCFUAHRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415571   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM415571((2R,3R,4S,5R)-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  30nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent