BDBM415633 US10428108, Example 44

SMILES COc1ccc(C[C@H](NC(=O)COc2cc(Cl)cc(Cl)c2)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)C(=O)NCC(F)(F)F)cc1OC

InChI Key InChIKey=LMVLCERVEYMMFF-CVDCTZTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415633   

TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM415633(US10428108, Example 44)
Affinity DataIC50:  140nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent