BDBM415693 US10442759, Compound I-5

SMILES COc1ccc(cc1OC)S(=O)(=O)N(CC(O)=O)c1ccc(OC(C(O)=O)c2ccccc2)c2ccccc12

InChI Key InChIKey=QBRITQNCHBPZKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 415693   

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM415693(US10442759, Compound I-5)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
China Pharmaceutical University

US Patent
LigandPNGBDBM415693(US10442759, Compound I-5)
Affinity DataIC50:  2.30E+3nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent