BDBM416659 US10323013, Compound 37::allyl 7-(3-ethoxy-3-oxoprop-1-en-1-yl)-8-hydroxy-5-oxo-4,5-dihydro-1H-chromeno[3,4-c]pyridine-3(2H)-carboxylate

SMILES CCOC(=O)C=Cc1c(O)ccc2c3CCN(Cc3c(=O)oc12)C(=O)OCC=C

InChI Key InChIKey=FAIBBTYZEZBWKU-SOFGYWHQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416659   

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM416659(US10323013, Compound 37 | allyl 7-(3-ethoxy-3-oxop...)
Affinity DataIC50:  1.72E+3nMAssay Description:All compounds were evaluated by FRET-suppression assay in side-by-side experiments using 21b as a control inhibitor (Table 2). Protection of the alde...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent