BDBM416724 N-((1s,4s)-4-(4-amino-7-oxo-3-(4- phenoxyphenyl)-6,7-dihydro-1H- pyrrolo[2,3-d]pyridazin-1- yl)cyclohexyl)acrylamide::US10323037, Example 11

SMILES Nc1n[nH]c(=O)c2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NC(=O)C=C

InChI Key InChIKey=XHXBDYNLATZPDC-KDURUIRLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416724   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM416724(N-((1s,4s)-4-(4-amino-7-oxo-3-(4- phenoxyphenyl)-6...)
Affinity DataIC50:  505nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent