BDBM417072 US10456394, Example 8
SMILES ONC(=O)c1ccc(CN2CCCc3cc(Cl)c(F)cc23)cc1
InChI Key InChIKey=XOJVBRCAEOFWNA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 417072
TargetHistone deacetylase 1(Homo sapiens (Human))
The Board Of Trustees Of The University Of Illinois
US Patent
The Board Of Trustees Of The University Of Illinois
US Patent
Affinity DataIC50: 3.22E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of full length recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
The Board Of Trustees Of The University Of Illinois
US Patent
The Board Of Trustees Of The University Of Illinois
US Patent
Affinity DataIC50: 4.80nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair