BDBM417072 US10456394, Example 8

SMILES ONC(=O)c1ccc(CN2CCCc3cc(Cl)c(F)cc23)cc1

InChI Key InChIKey=XOJVBRCAEOFWNA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 417072   

TargetHistone deacetylase 1(Homo sapiens (Human))
The Board Of Trustees Of The University Of Illinois

US Patent
LigandPNGBDBM417072(US10456394, Example 8)
Affinity DataIC50:  3.22E+3nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM417072(US10456394, Example 8)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of full length recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
The Board Of Trustees Of The University Of Illinois

US Patent
LigandPNGBDBM417072(US10456394, Example 8)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 insect cells using RHKKAc fluorogenic peptide as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM417072(US10456394, Example 8)
Affinity DataIC50:  4.80nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent