BDBM417932 2-(6-{5-chloro-2- [(oxan-4- yl)amino]pyrimidin-4- yl}-1-oxo-2,3-dihydro- 1H-isoindol-2-yl)-N- [(1S,2S)-1-(3-fluoro-5- methylphenyl)-2- hydroxypropyl] acetamide::US10457669, Example 588

SMILES C[C@H](O)C(NC(=O)CN1Cc2ccc(cc2C1=O)-c1nc(NC2CCOCC2)ncc1Cl)c1cc(C)cc(F)c1

InChI Key InChIKey=FRVXMZVAAPVVKW-WFFHQLTOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 417932   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417932(2-(6-{5-chloro-2- [(oxan-4- yl)amino]pyrimidin-4- ...)
Affinity DataIC50:  2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent