BDBM418468 5-(3-Fluoro-2-methylphenyl)-1-(4-fluorobenzyl)-N- hydroxy-4,5,6,7-tetrahydro-1H-indazole-5- carboxamide and 5-(3-fluoro-2-methylphenyl)-2-(4- fluorobenzyl)-N-hydroxy-4,5,6,7-tetrahydro-2H- indazole-5-carboxamide::US10457675, Example 36

SMILES Cc1c(F)cccc1C1(CCc2c(C1)cnn2Cc1ccc(F)cc1)C(=O)NO

InChI Key InChIKey=OHNMDIUCNOCIPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418468   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM418468(5-(3-Fluoro-2-methylphenyl)-1-(4-fluorobenzyl)-N- ...)
Affinity DataIC50:  600nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent