BDBM418505 7-Methoxy-3-methyl-8-(1- methyl-1H-pyrazol-4-yl)-1- (1H-pyrrolo[2,3-b]pyridin-6- yl)1,3-dihydroimidazo- [4,5-c]quinolin-2-one::US10457677, Example 69::US10975075, Example 69::US11608338, Example 69

SMILES COc1cc2ncc3n(C)c(=O)n(-c4ccc5cc[nH]c5n4)c3c2cc1-c1cnn(C)c1

InChI Key InChIKey=ZWNLRXJOHJINDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 418505   

TargetSerine-protein kinase ATM(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM418505(7-Methoxy-3-methyl-8-(1- methyl-1H-pyrazol-4-yl)-1...)
Affinity DataIC50: <1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM418505(7-Methoxy-3-methyl-8-(1- methyl-1H-pyrazol-4-yl)-1...)
Affinity DataIC50: <1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM418505(7-Methoxy-3-methyl-8-(1- methyl-1H-pyrazol-4-yl)-1...)
Affinity DataIC50: <1nMAssay Description:The IC50 value was determined with the aid of a biochemical ATM kinase assay. The assay consists of two steps: the enzymatic reaction and the detecti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent