BDBM419149 2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6′-((1-methyl-1H-pyrazol-4-yl)methylamino)-1′H-spiro[cyclopropane-1,4′-[2,7]naphthyridin]-3′(2′H)-one::US10450313, Example 37

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(NCc4ccn(C)c4)cc3C3(CC3)C2=O)c1F

InChI Key InChIKey=DCWMVDNRYPTWAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419149   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM419149(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM419149(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM419149(2′-(2,6-difluoro-3,5-dimethoxyphenyl)-6̸...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent