BDBM419796 US10464919, Example 134

SMILES Clc1cc(N2CCN(Cc3ccc4c5NCCCc5c(=O)[nH]c4c3)CC2)c(cn1)C#N

InChI Key InChIKey=UWIOUEAALWYOMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419796   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419796(US10464919, Example 134)
Affinity DataIC50:  12.2nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419796(US10464919, Example 134)
Affinity DataIC50:  2.70nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419796(US10464919, Example 134)
Affinity DataIC50:  4.15nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent